circRNA basic information
circBase ID: -
Name: hsa_circ_EEF2
Synonym: -
Host Gene: hsa-miR-6881-3p
 
 
 
Disease basic information
DO ID:
2152
DO name: ovary epithelial cancer
Disease details: epithelial ovarian cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: A2780, SKOV3
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: ANXA2
Associated microRNA: hsa-miR-6881-3p
Biological function: promoted autophagy, proliferation, and invasion
Molecular mechanism: interacting with hsa-miR-6881-3p and ANXA2
Survival: -
Supported No.:
1
Description:

circEEF2 could directly bind with ANXA2 to inhibit the expression of p-mTOR. In conclusion, findings of the current study illustrate that circEEF2 promoted autophagy, proliferation, and invasion of EOC by interacting with miR-6881-3p and ANXA2.

Other information
Title:

Circ-EEF2 facilitated autophagy via interaction with mir-6881-3p and ANXA2 in EOC.

Journal: Am J Cancer Res
Published: 2020/12/10
PubMed ID: 33294264