circRNA basic information
circBase ID: -
Name: hsa_circ_ASAP2
Synonym: -
Host Gene: hsa-miR-770-5p
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: AGS, MKN45
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: CDK6
Associated microRNA: hsa-miR-770-5p
Biological function: promotes cell viability, migration, and invasion of gastric cancer cells
Molecular mechanism: regulating the hsa-miR-770-5p/CDK6 axis
Survival: -
Supported No.:
 3
Description:

Circ_ASAP2 knockdown can repress the development of GC cells partly through regulating the miR-770-5p/CDK6 axis, suggesting an underlying circRNA-targeted therapy for GC treatment.
Other information
Title:

Circular RNA circ_ASAP2 promotes cell viability, migration, and invasion of gastric cancer cells by regulating the miR-770-5p/CDK6 axis.

Journal: Int J Clin Exp Pathol
Published: 2020/12/8
PubMed ID: 33284890