circRNA basic information
circBase ID: hsa_circ_0002483
Name: -
Synonym: circ_0002483
Host Gene: hsa-miR-758-3p
 
 
 
Disease basic information
DO ID:
 9119
DO name: acute myeloid leukemia
Disease details: acute myeloid leukemia
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: HL-60, AML-193
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: MYC
Associated microRNA: hsa-miR-758-3p
Biological function: Circ_0002483 knockdown repressed AML cell proliferation and promoted cycle arrest and apoptosis
Molecular mechanism: controlling hsa-miR-758-3p/MYC axis
Survival: -
Supported No.:
 1
Description:

miR-758-3p overexpression restrained cell proliferation and promoted cycle arrest and apoptosis via decreasing MYC. Circ_0002483 knockdown repressed AML cell proliferation and promoted cycle arrest and apoptosis via controlling miR-758-3p/MYC axis.
Other information
Title:

Hsa_circ_0002483 regulates miR-758-3p/MYC axis to promote acute myeloid leukemia progression.

Journal: Hematol Oncol
Published: 2020/12/8
PubMed ID: 33283885