circRNA basic information
circBase ID: -
Name: hsa_circ_GSK3B
Synonym: -
Host Gene: hsa-miR-1265
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: HOS, U2OS, SJSA1, Saos2, MG63
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: CAB39
Associated microRNA: hsa-miR-1265
Biological function: Promotes Cell Proliferation, Migration, and Invasion
Molecular mechanism: Sponging hsa-miR-1265 and Regulating CAB39 Expression
Survival: -
Supported No.:
 1
Description:

circGSK3B-miR-1265-CAB39 axis can promote the proliferation, migration, invasion of HCC cells, indicating that circGSKB may serve as a promising diagnostic and prognostic marker in HCC.
Other information
Title:

Circular RNA circGSK3B Promotes Cell Proliferation, Migration, and Invasion by Sponging miR-1265 and Regulating CAB39 Expression in Hepatocellular Carcinoma.

Journal: Front Oncol
Published: 2020/12/3
PubMed ID: 33262952