circRNA basic information
circBase ID: -
Name: hsa_circ_USP36
Synonym: -
Host Gene: hsa-miR-98-5p
 
 
 
Disease basic information
DO ID:
 1936
DO name: atherosclerosis
Disease details: atherosclerosis
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: HPMECs, BEAS-2B
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: VCAM1
Associated microRNA: hsa-miR-98-5p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 7
Description:

Ox-LDL promoted the apoptosis and inflammation but suppressed the viability of HUVEC cells through upregulating circ-USP36, thus elevating the expression of VCAM1 via miR-98-5p.
Other information
Title:

Oxidized low-density lipoprotein accelerates the injury of endothelial cells via circ-USP36/miR-98-5p/VCAM1 axis.

Journal: IUBMB Life
Published: 2020/11/30
PubMed ID: 33249762