circRNA basic information
circBase ID: hsa_circ_0004507
Name: -
Synonym: circ_0004507
Host Gene: hsa-miR-873
 
 
 
Disease basic information
DO ID:
 2600
DO name: laryngeal carcinoma
Disease details: laryngeal cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: AMC-HN-8, Tu-177
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-873
Biological function: contributes to laryngeal cancer progression and cisplatin resistance
Molecular mechanism: sponging hsa-miR-873 to upregulate multidrug resistance 1 and multidrug resistance protein 1
Survival: -
Supported No.:
 1
Description:

Knockdown of circ_0004507 inhibited laryngeal cancer progression and cisplatin resistance by sponging miR-873, providing a potential target for laryngeal cancer therapy.
Other information
Title:

Circular RNA circ_0004507 contributes to laryngeal cancer progression and cisplatin resistance by sponging miR-873 to upregulate multidrug resistance 1 and multidrug resistance protein 1.

Journal: Head Neck
Published: 2020/11/29
PubMed ID: 33247530