circRNA basic information
circBase ID: hsa_circ_0000284
Name: hsa_circ_HIPK3
Synonym: -
Host Gene: hsa-miR-338-3p
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: HepG2, Hep3B, Huh-7, SK-Hep1
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: ZEB2
Associated microRNA: hsa-miR-338-3p
Biological function: promotes cell migration, invasion, and metastases
Molecular mechanism: sponging hsa-miR-338-3p to induce ZEB2 expression
Survival: -
Supported No.:
 6
Description:

CircHIPK3 plays a regulatory role in metastatic HCC by sponging miR-338-3p to induce ZEB2 expression, thus promoting EMT procession.
Other information
Title:

HIPK3 Circular RNA Promotes Metastases of HCC Through Sponging miR-338-3p to Induce ZEB2 Expression.

Journal: Dig Dis Sci
Published: 2020/11/29
PubMed ID: 33247421