circRNA basic information
circBase ID: -
Name: hsa_circ_RIMS1
Synonym: -
Host Gene: hsa-miR-433-3p
 
 
 
Disease basic information
DO ID:
 11054
DO name: urinary bladder cancer
Disease details: bladder cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: HEK293 cells, human immortalized uroepithelium cell line (SV-HUC-1), human bladder cancer cell lines (J82, 5637, T24, EJ, TCCSUP)
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
UP
Associated gene: CCAR1
Associated microRNA: hsa-miR-433-3p
Biological function: Inhibition of circRIMS1 suppressed the proliferation, migration, and invasion of bladder cancer cells
Molecular mechanism: circRIMS1/hsa-miR-433-3p/CCAR1 regulatory axis
Survival: -
Supported No.:
 1
Description:

our research demonstrated that circRIMS1 promotes tumor growth, migration, and invasion through the miR-433-3p/CCAR1 regulatory axis, representing a potential therapeutic target and biomarker in bladder cancer.
Other information
Title:

Circular RNA circRIMS1 Acts as a Sponge of miR-433-3p to Promote Bladder Cancer Progression by Regulating CCAR1 Expression.

Journal: Mol Ther Nucleic Acids
Published: 2020/11/25
PubMed ID: 33230478