circRNA basic information
circBase ID: hsa_circ_0020397
Name: hsa_circ_DOCK1
Synonym: -
Host Gene: hsa-miR-138
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: cell line
Sample type details: normal human colonic epithelial cells (CCD 841 CoN), colorectal cell lines (LoVo, HCT116, SW480, SW620)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: TERT, PD-L1
Associated microRNA: hsa-miR-138
Biological function: promoted cell viability and invasion of CRC cells and inhibited their apoptosis
Molecular mechanism: promoting the expression of the hsa-miR-138 targets TERT and PD-L1
Survival: poor
Supported No.:
 4
Description:

Hsa_circ_0020397 can regulate colorectal cancer (CRC) cell viability, apoptosis, and invasion by promoting the expression of miR-138 target genes.
Other information
Title:

Hsa_circ_0020397 regulates colorectal cancer cell viability, apoptosis and invasion by promoting the expression of the miR-138 targets TERT and PD-L1.

Journal: Cell Biol Int
Published: 2017/7/15
PubMed ID: 28707774