circRNA basic information
circBase ID: -
Name: hsa_circ_PSD3
Synonym: -
Host Gene: hsa-miR-637
 
 
 
Disease basic information
DO ID:
 3969
DO name: thyroid gland papillary carcinoma
Disease details: papillary thyroid cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: TPC-1, CGTH-W3, IHH-4, SW579
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: HEMGN
Associated microRNA: hsa-miR-637
Biological function: promoted the cell cycle progression, proliferation and metastasis and impeded the apoptosis of PTC cells
Molecular mechanism: via the hsa-miR-637/HEMGN axis
Survival: -
Supported No.:
 5
Description:

Circ_PSD3 promoted the progression of PTC through regulating miR-637/HEMGN axis and activating PI3K/Akt signaling. Circ_PSD3/miR-637/HEMGN signaling axis might be a potential target for PTC therapy.
Other information
Title:

Circ_PSD3 promotes the progression of papillary thyroid carcinoma via the miR-637/HEMGN axis.

Journal: Life Sci
Published: 2020/11/19
PubMed ID: 33203523