circRNA basic information
circBase ID: -
Name: hsa_circ_MCTP2
Synonym: -
Host Gene: hsa-miR-99a-5p
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: BGC823, SGC7901, SGC7901
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
DN
Associated gene: MTMR3
Associated microRNA: hsa-miR-99a-5p
Biological function: inhibits cisplatin resistance
Molecular mechanism: through the upregulation of MTMR3 by sponging hsa-miR-99a-5p
Survival: -
Supported No.:
 1
Description:

CircMCTP2 sensitizes GC to CDDP through the upregulation of MTMR3 by sponging miR-99a-5p. Overexpression of CircMCTP2 could be a new therapeutic strategy for counteracting CDDP resistance in GC.
Other information
Title:

Circular RNA MCTP2 inhibits cisplatin resistance in gastric cancer by miR-99a-5p-mediated induction of MTMR3 expression.

Journal: J Exp Clin Cancer Res
Published: 2020/11/18
PubMed ID: 33198772