circRNA basic information
circBase ID: -
Name: hsa_circ_RPPH1
Synonym: -
Host Gene: hsa-miR-556-5p
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: MCF-7, MDA-MB-231
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: YAP1
Associated microRNA: hsa-miR-556-5p
Biological function: promoted the proliferation, migration, invasion, and angiogenesis of breast cancer cell lines and tumor growth in vivo
Molecular mechanism: via the hsa-miR-556-5p/YAP1 axis
Survival: -
Supported No.:
 9
Description:

Our data reveal that circRPPH1 plays a vital regulatory role in breast cancer via the miR-556-5p/YAP1 axis and may serve as a promising therapeutic target for breast cancer treatment.
Other information
Title:

Circular RNA circRPPH1 promotes triple-negative breast cancer progression via the miR-556-5p/YAP1 axis.

Journal: Am J Transl Res
Published: 2020/11/17
PubMed ID: 33194025