circRNA basic information
circBase ID: hsa_circ_0057553
Name: -
Synonym: circ_0057553
Host Gene: hsa-miR-515-5p
 
 
 
Disease basic information
DO ID:
 10283
DO name: prostate cancer
Disease details: prostate cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: 22RV1, PC3, DU145, LNCap
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: YES1
Associated microRNA: hsa-miR-515-5p
Biological function: Knockdown of circ_0057553 inhibited cell viability, migration, invasion and glycolysis and facilitated apoptosis in PCa cells.
Molecular mechanism: bound to hsa-miR-515-5p and hsa-miR-515-5p directly targeted YES1
Survival: -
Supported No.:
 1
Description:

Circ_0057553 affected PCa cell viability, migration, invasion, apoptosis and glycolysis through miR-515-5p/YES1 axis.
Other information
Title:

Circ_0057553/miR-515-5p Regulates Prostate Cancer Cell Proliferation, Apoptosis, Migration, Invasion and Aerobic Glycolysis by Targeting YES1.

Journal: Onco Targets Ther
Published: 2020/11/13
PubMed ID: 33177837