circRNA basic information
circBase ID: hsa_circ_0067835
Name: hsa_circ_IFT80
Synonym: -
Host Gene: hsa-miR-324-5p
 
 
 
Disease basic information
DO ID:
 1380
DO name: endometrial cancer
Disease details: endometrial cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: Ishikawa, HEC1-B, RL95-2 cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: HMGA1
Associated microRNA: hsa-miR-324-5p
Biological function: promote proliferation, migration and invasion
Molecular mechanism: compete with hsa-miR-324-5p, resulting in HMGA1 up-regulation,
Survival: -
Supported No.:
 2
Description:

circ_0067835 can compete with miR-324-5p, resulting in HMGA1 up-regulation, and therefore induce the development of endometrial cancer.
Other information
Title:

Circ_0067835 sponges miR-324-5p to induce HMGA1 expression in endometrial carcinoma cells.

Journal: J Cell Mol Med
Published: 2020/11/11
PubMed ID: 33169939