circRNA basic information
circBase ID: hsa_circ_0075370
Name: hsa_circ_MGAT1
Synonym: -
Host Gene: hsa-miR-34a
 
 
 
Disease basic information
DO ID:
 1682
DO name: congenital heart disease
Disease details: congenital heart disease
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: AC16
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: YAP1
Associated microRNA: hsa-miR-34a
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

circMGAT1 sponged miR-34a to regulate the expression of YAP1. In conclusion, circMGAT1 inhibited cell apoptosis and enhanced cell proliferation by regulating the miR-34a/YAP1 axis, providing a therapy target for the treatment of human CHD.
Other information
Title:

Circular RNA MGAT1 regulates cell proliferation and apoptosis in hypoxia-induced cardiomyocytes through miR-34a/YAP1 axis.

Journal: Int J Clin Exp Pathol
Published: 2020/11/10
PubMed ID: 33165436