circRNA basic information
circBase ID: -
Name: hsa_circ_PRKCI
Synonym: -
Host Gene: hsa-miR-150-5p
 
 
 
Disease basic information
DO ID:
 1324
DO name: lung cancer
Disease details: lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: SPC-A1, A549, H1299, H460
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: MECP2
Associated microRNA: hsa-miR-150-5p
Biological function: inhibition of circ-PRKCI in LCa cell lines remarkably inhibited cell invasiveness and proliferation
Molecular mechanism: modulates the progression of LCa through microRNA-150-5p/MECP2 axis
Survival: poor
Supported No.:
 3
Description:

Our study shows for the first time that circ-PRKCI modulates the progression of LCa through microRNA-150-5p/MECP2 axis.
Other information
Title:

Circular RNA circ-PRKCI promotes lung cancer progression by binding to microRNA-1324 to regulate MECP2 expression.

Journal: Eur Rev Med Pharmacol Sci
Published: 2020/11/7
PubMed ID: 33155212