circRNA basic information
circBase ID: hsa_circ_0043278
Name: hsa_circ_TADA2A
Synonym: -
Host Gene: hsa-miR-638
 
 
 
Disease basic information
DO ID:
 3073
DO name: brain glioblastoma multiforme
Disease details: glioblastoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: U87, U251, A172, U373
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: HOXA9
Associated microRNA: hsa-miR-638
Biological function: while knockdown circ_0043278 inhibited GBM cell migration, proliferation, and invasion invitro and tumorigenesis invivo
Molecular mechanism: directly sponged hsa-miR-638 to upregulate the expression of HOXA9
Survival: -
Supported No.:
 1
Description:

circ-0043278/miRNA-638/ Homeobox A9 (HOXA9) axis had a vital function in promoting GBM progression. Our findings may provide potential new targets for the diagnosis and therapy of GBM.
Other information
Title:

Hsa_circ_0043278 functions as competitive endogenous RNA to enhance glioblastoma multiforme progression by sponging miR-638.

Journal: Aging (Albany NY)
Published: 2020/11/7
PubMed ID: 33154193