circRNA basic information
circBase ID: hsa_circ_0007364
Name: hsa_circ_PTP4A2
Synonym: -
Host Gene: hsa-miR-101-5p
 
 
 
Disease basic information
DO ID:
 4362
DO name: cervical cancer
Disease details: cervical cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: HeLa, CaSki, SiHa, C-33A, C-4I, SW756
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: MAT2A
Associated microRNA: hsa-miR-101-5p
Biological function: inhibition notably suppressed the proliferation and invasion abilities of CC cells in vitro and reduced tumor growth in vivo
Molecular mechanism: activating methionine adenosyltransferase II alpha (MAT2A) expression by restraining microRNA-101-5p
Survival: -
Supported No.:
 1
Description:

hsa_circ_0007364 might serve as an oncogenic circRNA in CC progression by regulating the miR-101-5p/MAT2A axis, which provides a potential therapeutic target to the treatment. Research highlights hsa_circ_0007364 was upregulated in CC hsa_circ_0007364 promoted CC cell progression hsa_circ_0007364/miR-101-5p/MAT2A axis in CC.
Other information
Title:

Circular RNA hsa_circ_0007364 increases cervical cancer progression through activating methionine adenosyltransferase II alpha (MAT2A) expression by restraining microRNA-101-5p.

Journal: Bioengineered
Published: 2020/11/4
PubMed ID: 33138667