circRNA basic information
circBase ID: -
Name: -
Synonym: circ_001504
Host Gene: hsa-miR-149
 
 
 
Disease basic information
DO ID:
 4451
DO name: renal carcinoma
Disease details: renal carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: NUCB2
Associated microRNA: hsa-miR-149
Biological function: promotes the development of renal cell carcinoma
Molecular mechanism: sponging microRNA-149 to increase NUCB2
Survival: -
Supported No.:
 1
Description:

reduced expression of circ_001504 lowered NUCB2 expression by sponging miR-149, thereby attenuating RCC progression, providing insight into circ_001504/miR-149/NUCB2 feedback loop into RCC treatment.
Other information
Title:

circ_001504 promotes the development of renal cell carcinoma by sponging microRNA-149 to increase NUCB2.

Journal: Cancer Gene Ther
Published: 2020/10/29
PubMed ID: 33110207