circRNA basic information
circBase ID: hsa_circ_0002402
Name: hsa_circ_ECE1
Synonym: -
Host Gene: -
 
 
 
Disease basic information
DO ID:
 3347
DO name: osteosarcoma
Disease details: osteosarcoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: MG-63, U2OS, SJSA-1, HOS, 143B
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: c-Myc
Associated microRNA: -
Biological function: -
Molecular mechanism: -
Survival: -
Supported No.:
 2
Description:

CircECE1 regulates the Warburg effect through the c-Myc/TXNIP axis. CircECE1 mediated signal transduction plays a important role in OS process and energy metabolism. These findings may identify novel targets for OS molecular therapy.
Other information
Title:

CircECE1 activates energy metabolism in osteosarcoma by stabilizing c-Myc.

Journal: Mol Cancer
Published: 2020/10/28
PubMed ID: 33106166