circRNA basic information
circBase ID: -
Name: hsa_circ_sSMARCA5
Synonym: -
Host Gene: hsa-miR-670-5p
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: H1299, H1975, H1650, PC9, SPC-A1, A549
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: RBM24
Associated microRNA: hsa-miR-670-5p
Biological function: inhibited tumor growth in vivo, reduced cell proliferation and increased cell apoptosis in vitro
Molecular mechanism: negatively regulate hsa-miR-670-5p and had positive relationship with RBM24
Survival: -
Supported No.:
 1
Description:

circsSMARCA5 may serve as an NSCLC suppressor by regulating the miR-670-5p/RBM24 axis, and it may have the potential to be a biomarker or therapeutic target for NSCLC.
Other information
Title:

Circular RNA SMARCA5 suppressed non-small cell lung cancer progression by regulating miR-670-5p/RBM24 axis.

Journal: Acta Biochim Biophys Sin (Shanghai)
Published: 2020/10/22
PubMed ID: 33085761