circRNA basic information
circBase ID: hsa_circ_0102231
Name: -
Synonym: -
Host Gene: hsa-miR-145
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: cell line
Sample type details: A549, NCI-H358, NCI-H1650, HCC827, NCI-H1299
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: RBBP4
Associated microRNA: hsa-miR-145
Biological function: promotes proliferation and invasion
Molecular mechanism: mediating the hsa-miR-145/RBBP4 axis
Survival: -
Supported No.:
 1
Description:

hsa_circ_0102231 promotes proliferation and invasion by mediating the miR-145/RBBP4 axis in NSCLC, indicating that it might be a potential target for NSCLC treatment.
Other information
Title:

Circular RNA hsa_circ_0102231 sponges miR-145 to promote non-small cell lung cancer cell proliferation by up-regulating the expression of RBBP4.

Journal: J Biochem
Published: 2020/10/22
PubMed ID: 33084863