circRNA basic information
circBase ID: hsa_circ_0072088
Name: -
Synonym: circ_0072088
Host Gene: hsa-miR-377
 
 
 
Disease basic information
DO ID:
 3748
DO name: esophagus squamous cell carcinoma
Disease details: esophageal squamous cell carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: TE-13, Kyse150, ECA109, Kyse450, Kyse510
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: VEGF
Associated microRNA: hsa-miR-377
Biological function: Promotes Proliferation, Migration, and Invasion
Molecular mechanism: upregulated VEGF gene expression by acting as the sponge of miRNA-377
Survival: poor
Supported No.:
 1
Description:

circ_0072088 upregulated VEGF gene expression by acting as the sponge of miRNA-377. In conclusion, circ_0072088 might be used as a diagnostic biomarker and therapeutic target for ESCC.
Other information
Title:

Circ_0072088 Promotes Proliferation, Migration, and Invasion of Esophageal Squamous Cell Cancer by Absorbing miR-377.

Journal: J Oncol
Published: 2020/10/17
PubMed ID: 33061973