circRNA basic information
circBase ID: -
Name: hsa_circ_ASAP2
Synonym: -
Host Gene: hsa-miR-33a-5p
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: cell line, PDX
Sample type details: human gastric cancer cell lines (AGS, HGC-27), human normal gastric epithelial cell line (GES-1)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: CDK7
Associated microRNA: hsa-miR-33a-5p
Biological function: promoted cell proliferation, migration and invasion, whereas inhibited cell apoptosis
Molecular mechanism: upregulating CDK7 expression through binding to hsa-miR-33a-5p
Survival: -
Supported No.:
 3
Description:

Circ_ASAP2 overexpression promoted cell proliferation, migration and invasion, whereas inhibited cell apoptosis by upregulating CDK7 expression through binding to miR-33a-5p in GA-induced GC cells. This study provided a theoretical basis in GC treatment with GA.
Other information
Title:

Gambogic Acid Inhibits the Progression of Gastric Cancer via circRNA_ASAP2/miR-33a-5p/CDK7 Axis.

Journal: Cancer Manag Res
Published: 2020/10/17
PubMed ID: 33061613