circRNA basic information
circBase ID: -
Name: hsa_circ_ITCH
Synonym: cir-ITCH, circ-ITCH
Host Gene: hsa-miR-17
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: GES-1
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: -
Associated microRNA: hsa-miR-17
Biological function: inhibits gastric cancer migration, invasion and proliferation
Molecular mechanism: sponging hsa-miR-17
Survival: better
Supported No.:
 3
Description:

cir-ITCH was shown to prevent gastric cancer tumourgenesis through the Wnt/beta-catenin signalling pathway by sequestering miR-17.
Other information
Title:

Cir-ITCH inhibits gastric cancer migration, invasion and proliferation by regulating the Wnt/beta-catenin pathway.

Journal: Sci Rep
Published: 2020/10/17
PubMed ID: 33060778