circRNA basic information
circBase ID: hsa_circ_0001785
Name: hsa_circ_ELP3
Synonym: -
Host Gene: hsa-miR-942
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: T47D, MCF-7, MDA-MB-453, MDA-MB-231, BT-549
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: SOCS3
Associated microRNA: hsa-miR-942
Biological function: inhibits the proliferation, migration and invasion of breast cancer cells
Molecular mechanism: sponging hsa-miR-942 to upregulate SOCS3
Survival: -
Supported No.:
 3
Description:

circ_0001785 has low expression in BC. Circ_0001785 overexpression significantly inhibited cell proliferation, migration/invasion and the tumor growth.

Other information
Title:

Circular RNA hsa_circ_0001785 inhibits the proliferation, migration and invasion of breast cancer cells in vitro and in vivo by sponging miR-942 to upregulate SOCS3.

Journal: Cell Cycle
Published: 2020/10/16
PubMed ID: 33054543