circRNA basic information
circBase ID: hsa_circ_0086996
Name: hsa_circ_RECK
Synonym: -
Host Gene: hsa-miR-125b-5p
 
 
 
Disease basic information
DO ID:
 3347
DO name: osteosarcoma
Disease details: osteosarcoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: OB3, U2-OS, SAOS2, HOS, 143B, MG-63
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-125b-5p
Biological function: Circ_0086996 knockdown significantly suppressed cell proliferation, migration, and invasion
Molecular mechanism: acts as hsa-miR-125b-5p sponge
Survival: -
Supported No.:
 1
Description:

Circ_0086996 acts as miR-125b-5p sponge to mediate the tumorigenicity, which could act as a potential biomarker for the osteosarcoma and provides a novel insight for the mechanism in osteosarcoma.
Other information
Title:

Circular RNA 0086996 regulates growth and migration of osteosarcoma cells via miR-125b-5p.

Journal: Pathol Res Pract
Published: 2020/10/15
PubMed ID: 33053498