circRNA basic information
circBase ID: hsa_circ_0000043
Name: -
Synonym: circ_0000043
Host Gene: hsa-miR-136
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: MDA-MB-231, MCF7, ZR751
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: Smad3
Associated microRNA: hsa-miR-136
Biological function: promotes the proliferation, migration, invasiveness, and epithelial-mesenchymal transition
Molecular mechanism: up-regulate the expression of Smad3 by sponging hsa-miR-136.
Survival: -
Supported No.:
 1
Description:

Circ_0000043 promotes the proliferation, migration, invasiveness, and epithelial-mesenchymal transition in breast cancer cells via the miR-136-Smad3 axis.
Other information
Title:

Circ_0000043 promotes the proliferation, migration, invasiveness, and epithelial-mesenchymal transition in breast cancer cells via the miR-136-Smad3 axis.

Journal: Biochem Cell Biol
Published: 2020/10/13
PubMed ID: 33043682