circRNA basic information
circBase ID: -
Name: -
Synonym: chr7:154954255-154998784+
Host Gene: hsa-miR-4459
 
 
 
Disease basic information
DO ID:
 1793
DO name: pancreatic cancer
Disease details: pancreatic cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: PANC-1
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
UP
Associated gene: KIAA0513
Associated microRNA: hsa-miR-4459
Biological function: promotes the growth and metastasis
Molecular mechanism: targeting the hsa-miR-4459/KIAA0513 axis
Survival: -
Supported No.:
 1
Description:

Chr7:154954255-154998784+ may promote the development of pancreatic cancer through the miR-4459/KIAA0513 axis in CaPSCs and may be an important therapeutic target for patients with pancreatic cancer in the future.
Other information
Title:

Overexpression of circRNA chr7:154954255-154998784+ in cancer-associated pancreatic stellate cells promotes the growth and metastasis of pancreatic cancer by targeting the miR-4459/KIAA0513 axis.

Journal: Am J Transl Res
Published: 2020/10/13
PubMed ID: 33042405