circRNA basic information
circBase ID: -
Name: hsa_circ_PPM1F
Synonym: -
Host Gene: -
 
 
 
Disease basic information
DO ID:
 9744
DO name: type 1 diabetes mellitus
Disease details: type 1 diabetes mellitus
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: THP1
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: -
Molecular mechanism: -
Survival: -
Supported No.:
 1
Description:

Overexpression of circPPM1F could promote pancreatic islet injury by enhancing M1 macrophage activation and circPPM1F may serve as a novel potential therapeutic target for T1DM in children.
Other information
Title:

Circular RNA circPPM1F modulates M1 macrophage activation and pancreatic islet inflammation in type 1 diabetes mellitus.

Journal: Theranostics
Published: 2020/10/13
PubMed ID: 33042261