circRNA basic information
circBase ID: hsa_circ_0000285
Name: -
Synonym: circ_0000285
Host Gene: hsa-miR-409-3p
 
 
 
Disease basic information
DO ID:
3347
DO name: osteosarcoma
Disease details: osteosarcoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: hFOB 1.19, SJSA1, U2OS
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: IGFBP3
Associated microRNA: hsa-miR-409-3p
Biological function: promote proliferation, migration, invasion and inhibit apoptosis
Molecular mechanism: hsa-miR-409-3p/IGFBP3 axis
Survival: -
Supported No.:
2
Description:

circ_0000285 regulated proliferation, migration, invasion and apoptosis of OS cells by miR-409-3p/IGFBP3 axis, implying that circ_0000285 was a potential target for OS therapy.

Other information
Title:

Circ_0000285 regulates proliferation, migration, invasion and apoptosis of osteosarcoma by miR-409-3p/IGFBP3 axis.

Journal: Cancer Cell Int
Published: 2020/10/13
PubMed ID: 33041662