circRNA basic information
circBase ID: -
Name: -
Synonym: circ-102,166
Host Gene: hsa-miR-182, hsa-miR-184
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: Huh7, HepG2, 97H, SK-Hep1, Hep3B, LM3
circRNA-disease information
Detected method:
Q
S
M
Detected method confidence High
Expression pattern:
DN
Associated gene: -
Associated microRNA: hsa-miR-182, hsa-miR-184
Biological function: significantly inhibited the proliferation, invasion, migration and tumorigenicity of HCC cells
Molecular mechanism: acts as a sponge of hsa-miR-182 and hsa-miR-184
Survival: -
Supported No.:
 1
Description:

Our data revealed a tumor-suppressing role of circ-102,166 in HCC. Down-regulation of circ-102,166 enhanced the proliferation and invasion of HCC cells by releasing the oncomiRs miR-182 and miR-184.
Other information
Title:

Circular RNA circ-102,166 acts as a sponge of miR-182 and miR-184 to suppress hepatocellular carcinoma proliferation and invasion.

Journal: Cell Oncol (Dordr)
Published: 2020/10/10
PubMed ID: 33034848