circRNA basic information
circBase ID: -
Name: hsa_circ_ABCC4
Synonym: -
Host Gene: hsa-miR-154-5p
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: MDA-MB-231 , MCF-7
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-154-5p
Biological function: improve cell viability, migration and invasion
Molecular mechanism: up-regulating hsa-miR-154-5p via inhibiting NF-kappaB and Wnt/beta-catenin signal pathways
Survival: -
Supported No.:
 1
Description:

CircABCC4 knockdown repressed breast cancer cells viability, migration, and invasion by up-regulating miR-154-5p via inhibiting NF-kappaB and Wnt/beta-catenin signal pathways.
Other information
Title:

Circular RNA circABCC4 acts as a ceRNA of miR-154-5p to improve cell viability, migration and invasion of breast cancer cells in vitro.

Journal: Cell Cycle
Published: 2020/10/8
PubMed ID: 33023375