circRNA basic information
circBase ID: -
Name: hsa_circ_EXOC6B
Synonym: -
Host Gene: hsa-miR-376c-3p
 
 
 
Disease basic information
DO ID:
 2394
DO name: ovarian cancer
Disease details: ovarian cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: A2780, SKOV3
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: FOXO3
Associated microRNA: hsa-miR-376c-3p
Biological function: Suppresses the Proliferation and Motility and Sensitizes Ovarian Cancer Cells to Paclitaxel
Molecular mechanism: hsa-miR-376c-3p/FOXO3 Axis
Survival: -
Supported No.:
 2
Description:

CircEXOC6B suppressed the progression and PTX resistance of ovarian cancer cells through sequestering miR-376c-3p, thus enhancing FOXO3 level.
Other information
Title:

CircEXOC6B Suppresses the Proliferation and Motility and Sensitizes Ovarian Cancer Cells to Paclitaxel Through miR-376c-3p/FOXO3 Axis.

Journal: Cancer Biother Radiopharm
Published: 2020/10/3
PubMed ID: 33006481