circRNA basic information
circBase ID: -
Name: hsa_circ_FOXP1
Synonym: -
Host Gene: hsa-miR-33a-5p
 
 
 
Disease basic information
DO ID:
11476
DO name: osteoporosis
Disease details: osteoporosis
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: hASCs
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
DN
Associated gene: FOXP1
Associated microRNA: hsa-miR-33a-5p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
1
Description:

This research found that circFOXP1 was significantly down-regulated in OP patient bone tissues and functioned like a miRNA sponge targeting miR-33a-5p to increase FOXP1 expression.

Other information
Title:

CircFOXP1/FOXP1 promotes osteogenic differentiation in adipose-derived mesenchymal stem cells and bone regeneration in osteoporosis via miR-33a-5p.

Journal: J Cell Mol Med
Published: 2020/10/1
PubMed ID: 32996692