circRNA basic information
circBase ID: hsa_circ_0007031
Name: hsa_circ_TUBGCP3
Synonym: -
Host Gene: hsa-miR-760
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: DCP1A
Associated microRNA: hsa-miR-760
Biological function: Circ_0007031 knockdown hindered proliferation, induced cell cycle arrest in the G0/G1 phase, enhanced apoptosis, and lowered the CRR of CRC resistant cells
Molecular mechanism: regulating the hsa-miR-760/DCP1A axis
Survival: -
Supported No.:
 4
Description:

Circ_0007031 might play a positive role in the CRR of CRC through regulating the miR-760/DCP1A axis, which might provide a new approach for treating the CRR of CRC.
Other information
Title:

Circ_0007031 Serves as a Sponge of miR-760 to Regulate the Growth and Chemoradiotherapy Resistance of Colorectal Cancer via Regulating DCP1A.

Journal: Cancer Manag Res
Published: 2020/9/29
PubMed ID: 32982440