circRNA basic information
circBase ID: -
Name: hsa_circ_TTBK2
Synonym: -
Host Gene: hsa-miR-145-5p
 
 
 
Disease basic information
DO ID:
 0060108
DO name: brain glioma
Disease details: glioma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: T98G, LN229
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: CPEB4
Associated microRNA: hsa-miR-145-5p
Biological function: CircTTBK2 knockdown suppressed glioma cell proliferation, migration, invasion and glycolysis and accelerated apoptosis in vitro and hampered tumor growth in vivo
Molecular mechanism: functioned as a sponge of hsa-miR-145-5p
Survival: -
Supported No.:
 4
Description:

CircTTBK2 functioned as a tumor promoter in glioma by modulating miR-145-5p/CPEB4 axis, which might offer a new sight for glioma therapy.
Other information
Title:

CircTTBK2 Contributes to the Progression of Glioma Through Regulating miR-145-5p/CPEB4 Axis.

Journal: Cancer Manag Res
Published: 2020/9/29
PubMed ID: 32982415