circRNA basic information
circBase ID: -
Name: -
Synonym: circ_0062389
Host Gene: -
 
 
 
Disease basic information
DO ID:
 114
DO name: heart disease
Disease details: heart failure
Species: rat
Species details: rat
Sample type: tissue, cell line
Sample type details: H9C2
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: TGF-beta1/Smad3
Associated microRNA: -
Biological function: -
Molecular mechanism: -
Survival: -
Supported No.:
 1
Description:

Silencing circ_0062389 could alleviate cardiomyocyte apoptosis in HF rats via modulating TGF-beta1/Smad3 signaling pathway, which might be a promising target for the treatment of HF.
Other information
Title:

Silencing circ_0062389 alleviates cardiomyocyte apoptosis in heart failure rats via modulating TGF-beta1/Smad3 signaling pathway.

Journal: Gene
Published: 2020/9/20
PubMed ID: 32949699