circRNA basic information
circBase ID: hsa_circ_0000520
Name: hsa_circ_RPPH1
Synonym: -
Host Gene: -
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human BCa cell lines (T47D, MCF7, MDA-MB-231, BT549, SKBR3), normal breast epithelial cell line (MCF10A)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: promote Cell Growth, Migration and Invasion
Molecular mechanism: via hsa-miR-1296/SP1 Axis
Survival: poor
Supported No.:
 9
Description:

Circ_0000520 knockdown could suppress cell growth, migration and invasion both in vitro and in vivo through regulating miR-1296/SP1 pathway.
Other information
Title:

Blocking circ_0000520 Suppressed Breast Cancer Cell Growth, Migration and Invasion Partially via miR-1296/SP1 Axis Both in vitro and in vivo.

Journal: Cancer Manag Res
Published: 2020/9/15
PubMed ID: 32922078