circRNA basic information
circBase ID: -
Name: -
Synonym: circRNA2960
Host Gene: mmu-miR-124
 
 
 
Disease basic information
DO ID:
319
DO name: spinal cord disease
Disease details: spinal cord injury
Species: mouse
Species details: mouse
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: mmu-miR-124
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
1
Description:

A novel circRNA-2960 was the most significantly upregulated in the SCI group. It could downregulate its target molecule miRNA_124, then exacerbate the inflammatory response and induce apoptosis at the lesion site.

Other information
Title:

Novel circular RNA 2960 contributes to secondary damage of spinal cord injury by sponging miRNA-124.

Journal: J Comp Neurol
Published: 2020/9/13
PubMed ID: 32918278