circRNA basic information
circBase ID: -
Name: hsa_circ_ZNF292
Synonym: -
Host Gene: hsa-miR-23b-3p
 
 
 
Disease basic information
DO ID:
 0070353
DO name: cataract
Disease details: age-related cataract
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
DN
Associated gene: -
Associated microRNA: hsa-miR-23b-3p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

circZNF292, a down-regulated circRNA in the anterior lens capsule of ARC patients, may be involved in resistance to oxidative damage and apoptosis of lens epithelial cells by sponging miR-23b-3p, providing a potential target for prevention and treatment of ARC.
Other information
Title:

Profiling of circular RNAs in age-related cataract reveals circZNF292 as an antioxidant by sponging miR-23b-3p.

Journal: Aging (Albany NY)
Published: 2020/9/12
PubMed ID: 32913142