circRNA basic information
circBase ID: hsa_circ_0029589
Name: hsa_circ_CHFR
Synonym: -
Host Gene: hsa-miR-424-5p
 
 
 
Disease basic information
DO ID:
 1936
DO name: atherosclerosis
Disease details: atherosclerosis
Species: human
Species details: human
Sample type: cell line
Sample type details: human vascular smooth muscle cells (VSMCs)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: IGF2
Associated microRNA: hsa-miR-424-5p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 6
Description:

Circ_0029589 silence might inhibit the progression of AS by regulating miR-424-5p/IGF2 axis, providing a novel mechanism for pathogenesis of AS.
Other information
Title:

Circular RNA circ_0029589 regulates proliferation, migration, invasion, and apoptosis in ox-LDL-stimulated VSMCs by regulating miR-424-5p/IGF2 axis.

Journal: Vascul Pharmacol
Published: 2020/8/30
PubMed ID: 32860985