circRNA basic information
circBase ID: -
Name: hsa_circ_CCDC66
Synonym: -
Host Gene: hsa-miR-338-3p
 
 
 
Disease basic information
DO ID:
 3347
DO name: osteosarcoma
Disease details: osteosarcoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: SW1353, U2OS
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: PTP1B
Associated microRNA: hsa-miR-338-3p
Biological function: circCCDC66 knockdown promoted the inhibition of cell proliferation and metastatic of OS cell lines
Molecular mechanism: by hsa-miR-338-3p/PTP1B pathway
Survival: -
Supported No.:
 1
Description:

circCCDC66 contributed to malignant behaviors of OS cells by miR-338-3p/PTP1B pathway, which suggested circCCDC66/miR-338-3p/PTP1B axis might be a potential therapeutic target.
Other information
Title:

Circular RNA circCCDC66 Contributes to Malignant Phenotype of Osteosarcoma by Sponging miR-338-3p to Upregulate the Expression of PTP1B.

Journal: Biomed Res Int
Published: 2020/8/28
PubMed ID: 32851074