circRNA basic information
circBase ID: -
Name: hsa_circ_VAPA
Synonym: -
Host Gene: hsa-miR-615-3p
 
 
 
Disease basic information
DO ID:
 768
DO name: retinoblastoma
Disease details: retinoblastoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human retinal pigment epithelial cell line (ARPE-19), human RB cell lines (WERI Rb1, hTERT-RPE1, SO-RB-50, Y79)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: SMARCE1
Associated microRNA: hsa-miR-615-3p
Biological function: promoted RB proliferation and metastasis
Molecular mechanism: sponging hsa-miR-615-3p
Survival: -
Supported No.:
 1
Description:

circVAPA promoted RB proliferation and metastasis by sponging miR-615-3p, thereby upregulating SMARCE1. CircVAPA was a potential biomarker for Rb therapy.
Other information
Title:

The Potential Tumor Promotional Role of circVAPA in Retinoblastoma via Regulating miR-615-3p and SMARCE1.

Journal: Onco Targets Ther
Published: 2020/8/28
PubMed ID: 32848418