circRNA basic information
circBase ID: rno_circ_0005139
Name: -
Synonym: Rno_circ_0005139
Host Gene: mmu-miR-324-3p
 
 
 
Disease basic information
DO ID:
 1285
DO name: rectal disease
Disease details: anorectal malformation
Species: mouse
Species details: mouse
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
S
M
Detected method confidence High
Expression pattern:
DN
Associated gene: Wnt5a
Associated microRNA: mmu-miR-324-3p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

Rno_circ_0005139 influences cell proliferation and apoptosis by acting as a miR-324-3p sponge, thereby downregulating Wnt5a in ARM. Accordingly, rno_circ_0005139, miR-324-3p, and Wnt5a could be targeted therapeutic factors for ARM.
Other information
Title:

Rno_circ_0005139 regulates apoptosis by targeting Wnt5a in rat anorectal malformations.

Journal: World J Gastroenterol
Published: 2020/8/28
PubMed ID: 32848333