circRNA basic information
circBase ID: -
Name: mmu_circ_C3P1
Synonym: CircC3P1
Host Gene: mmu-miR-21
 
 
 
Disease basic information
DO ID:
0040085
DO name: bacterial sepsis
Disease details: sepsis
Species: mouse
Species details: mouse
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DS
Associated gene: -
Associated microRNA: mmu-miR-21
Biological function: CircC3P1 overexpression reduced cell apoptosis and pro-inflammatory cytokines levels
Molecular mechanism: via down-regulating miR-21
Survival: -
Supported No.:
1
Description:

CircC3P1 attenuated pro-inflammatory cytokine production and cell apoptosis in ALI induced by sepsis through modulating miR-21, indicating that circC3P1 is a promising therapeutic biomarker for sepsis-induced ALI

Other information
Title:

CircC3P1 attenuated pro-inflammatory cytokine production and cell apoptosis in acute lung injury induced by sepsis through modulating miR-21.

Journal: J Cell Mol Med
Published: 2020/8/28
PubMed ID: 32846020