circRNA basic information
circBase ID: hsa_circ_0008898
Name: hsa_circ_OAT
Synonym: -
Host Gene: hsa-miR-197-5p
 
 
 
Disease basic information
DO ID:
 50866
DO name: oral squamous cell carcinoma
Disease details: oral squamous cell carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: CAL27, SCC-25 cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: RHOA
Associated microRNA: hsa-miR-197-5p
Biological function: Knockdown of hsa_circ_0008898 inhibited OSCC cells proliferation, cloning, migration and invasion and induced cell cycle arrest in vitro
Molecular mechanism: regulating the hsa-miR-197-5p/RHOA
Survival: -
Supported No.:
 1
Description:

Knockdown of hsa_circ_0008898 inhibited OSCC cells proliferation, cloning, migration and invasion and induced cell cycle arrest in vitro by regulating the miR-197-5p/RHOA. Additionally, Knockdown of hsa_circ_0008898 also inhibited tumor formation of OSCC cells in vivo.
Other information
Title:

[Effect of circular RNA hsa_circ_0008898 on oral squamous cell carcinoma and its mechanism].

Journal: Zhonghua Kou Qiang Yi Xue Za Zhi
Published: 2020/8/28
PubMed ID: 32842350