circRNA basic information
circBase ID: hsa_circ_0079593
Name: hsa_circ_IGF2BP3
Synonym: -
Host Gene: hsa-miR-516b
 
 
 
Disease basic information
DO ID:
 1909
DO name: melanoma
Disease details: melanoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human normal epidermal melanocytes (PIG1), melanoma cell lines (A357, SK-MEL-2)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: GRM3
Associated microRNA: hsa-miR-516b
Biological function: facilitates proliferation, metastasis, glucose metabolism and inhibits apoptosis
Molecular mechanism: regulating the hsa-miR-516b/GRM3 axis
Survival: -
Supported No.:
 2
Description:

circ_0079593 accelerated melanoma progression via upregulating GRM3 by sponging miR-516b, which suggested that circ_0079593 had the potential to be a new therapeutic biomarker for melanoma.
Other information
Title:

Circ_0079593 facilitates proliferation, metastasis, glucose metabolism and inhibits apoptosis in melanoma by regulating the miR-516b/GRM3 axis.

Journal: Mol Cell Biochem
Published: 2020/8/26
PubMed ID: 32839935