circRNA basic information
circBase ID: hsa_circ_0011292
Name: hsa_circ_TINAGL1
Synonym: -
Host Gene: hsa-miR-379-5p
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: fetal lung fibroblast cell line (MRC5), NSCLC cell lines (A549, H1299)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: TRIM65
Associated microRNA: hsa-miR-379-5p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 2
Description:

Circ_0011292 facilitated tumorigenesis and PTX resistance in NSCLC by regulating the miR-379-5p/TRIM65 axis, suggesting that circ_0011292 was a promising therapeutic target for NSCLC chemotherapy.
Other information
Title:

Circ_0011292 Enhances Paclitaxel Resistance in Non-Small Cell Lung Cancer by Regulating miR-379-5p/TRIM65 Axis.

Journal: Cancer Biother Radiopharm
Published: 2020/8/25
PubMed ID: 32833503