circRNA basic information
circBase ID: hsa_circ_001436
Name: -
Synonym: -
Host Gene: hsa-miR-431-5p
 
 
 
Disease basic information
DO ID:
 1909
DO name: melanoma
Disease details: melanoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: A2058 cell
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: ROCK1/PI3K/AKT
Associated microRNA: hsa-miR-431-5p
Biological function: promoted cell proliferation and metastasis
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

circ 0001591 inhibits the progression of human melanoma through ROCK1/PI3K/AKT signal pathway by targeting ROCK1 by miR-431-5p.
Other information
Title:

Circular RNA has circ 0001591 promoted cell proliferation and metastasis of human melanoma via ROCK1/PI3K/AKT by targeting miR-431-5p.

Journal: Hum Exp Toxicol
Published: 2020/8/25
PubMed ID: 32830578